Across TCGA patient cohorts, INPP5B protein abundance is significantly associated with the RNA expression of many other genes, with 8,343 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible INPP5B-associated genes across cancer lineages are KLRG1, MYCBP, and COPZ2. Each is linked with INPP5B in more than 3 cancer types. Because this analysis shows association rather than direction, both INPP5B-to-partner and partner-to-INPP5B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5B→partner) and Y-score (partner→INPP5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KLRG1 →	+0.598	+0.282	<.001	.004	3	4
OV	MYCBP →	+0.521	+0.366	.008	.003	3	3
LSCC	COPZ2 →	-1.142	-0.398	<.001	.003	3	3
BRCA	PABPC4 →	+0.641	+0.390	<.001	<.001	3	3
COAD	AQP9 →	+1.509	+0.442	<.001	<.001	3	3
COAD	ETFB →	-0.608	-0.382	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,343 associations by consensus.

Exploration

INPP5B survival (RNA) · tumor vs normal (RNA) · all INPP5B data types