Across TCGA cell cohorts, INPP5B RNA expression is significantly associated with the RNA expression of many other genes, with 10,679 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INPP5B-associated genes across cancer lineages are THRAP3, SCMH1, and PIKFYVE. Each is linked with INPP5B in more than 15 cancer types. Because this analysis shows association rather than direction, both INPP5B-to-partner and partner-to-INPP5B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5B→partner) and Y-score (partner→INPP5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	THRAP3 →	+0.766	+0.879	<.001	<.001	3	16
BREAST	SCMH1 →	+1.006	+0.973	<.001	<.001	2	14
OVARY	PIKFYVE →	+0.937	+1.260	<.001	<.001	3	13
BLOOD_Lymphoma	ZMYM4 →	+0.931	+0.867	<.001	.002	2	13
BLOOD_Lymphoma	FOXJ3 →	+0.879	+1.016	<.001	<.001	2	13
LUNG_SCLC	KDM4A →	+1.016	+1.434	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,679 associations by consensus.

Exploration

INPP5B survival (RNA) · tumor vs normal (RNA) · all INPP5B data types