Across TCGA cell cohorts, INPP5B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,662 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INPP5B-associated GO terms across cancer lineages are Positive regulation of mRNA metabolic process, Centriole replication, and Mitotic spindle assembly. Each is linked with INPP5B in more than 9 cancer types. Because this analysis shows association rather than direction, both INPP5B-to-partner and partner-to-INPP5B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5B→partner) and Y-score (partner→INPP5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of mRNA metabolic process →	+0.054	+0.586	<.001	.003	3	10
OVARY	Centriole replication →	+0.080	+0.775	.001	.002	3	9
LUNG_NSCLC_LUSC	Mitotic spindle assembly →	+0.103	+0.839	.002	.007	3	9
SOFT_TISSUE	Microtubule organizing center organization →	+0.059	+0.499	<.001	.002	3	9
SOFT_TISSUE	Negative regulation of sister chromatid cohesion →	+0.106	+0.767	<.001	<.001	3	9
BLOOD_Lymphoma	Positive regulation of mRNA catabolic process →	+0.052	+0.747	.004	.008	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,662 associations by consensus.

Exploration

INPP5B survival (RNA) · tumor vs normal (RNA) · all INPP5B data types