INPP5A

Across TCGA patient cohorts, INPP5A protein abundance is significantly associated with the RNA expression of many other genes, with 16,023 significant associations in total. GBM shows the largest number of these associations.

The most reproducible INPP5A-associated genes across cancer lineages are WFDC1, ASPA, and CCDC18. Each is linked with INPP5A in more than 4 cancer types. Because this analysis shows association rather than direction, both INPP5A-to-partner and partner-to-INPP5A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INPP5A versus WFDC1 in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5A→partner) and Y-score (partner→INPP5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	WFDC1 →	+0.632	+0.607	.003	<.001	3	5
GBM	ASPA →	+1.023	+0.589	<.001	<.001	3	5
UCEC	CCDC18 →	-0.497	-0.272	.003	.005	3	5
CCRCC	DIPK2B →	+0.804	+0.290	<.001	<.001	3	5
BRCA	SLIT3 →	+1.000	+0.391	<.001	<.001	3	5
HNSC	GLUD1 →	+0.550	+0.209	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,023 associations by consensus.

INPP5A vs WFDC1 — GBM

Explore this scatter interactively →