INPP1

Across TCGA patient cohorts, INPP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,051 significant associations in total. GBM shows the largest number of these associations.

The most reproducible INPP1-associated proteins across cancer lineages are ADD3, TIMM9, and DGKA. Each is linked with INPP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both INPP1-to-partner and partner-to-INPP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INPP1 versus ADD3 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP1→partner) and Y-score (partner→INPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ADD3 →	+0.512	+0.708	<.001	<.001	3	5
OV	TIMM9 →	-0.428	-0.565	<.001	<.001	3	5
UCEC	DGKA →	+0.372	+0.641	<.001	<.001	3	4
OV	LIMA1_S490 →	+0.450	+0.373	.002	.005	3	4
OV	MRPS25 →	-0.441	-0.662	.001	<.001	3	4
COAD	MRPS26 →	-0.347	-0.631	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,051 associations by consensus.

INPP1 vs ADD3 — BRCA

Explore this scatter interactively →