INPP1

Across TCGA patient cohorts, INPP1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,845 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INPP1-associated genes across cancer lineages are CARD6, SAMD9, and PRDM8. Each is linked with INPP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both INPP1-to-partner and partner-to-INPP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INPP1 versus CARD6 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP1→partner) and Y-score (partner→INPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CARD6 →	+0.743	+0.376	<.001	.001	3	7
COAD	SAMD9 →	+1.258	+0.395	<.001	<.001	3	7
GBM	PRDM8 →	+0.887	+0.454	<.001	<.001	3	6
OV	ANTXR2 →	+0.934	+0.327	<.001	.005	3	6
LSCC	TMEM273 →	+0.646	+0.684	<.001	<.001	3	6
UCEC	IFNGR1 →	+0.572	+0.302	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,845 associations by consensus.

INPP1 vs CARD6 — BRCA

Explore this scatter interactively →