INO80E

Across TCGA pan-cancer cohorts, INO80E Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated INO80E data layer compared with 24 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher INO80E Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated INO80E expression acts as an unfavorable survival marker.

CESC, UCEC, and BLCA are the cancer types where INO80E Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	II,III,IV	0.068	0.830	<.001	24	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
BLCA	DFS	Median	III,IV	0.100	0.572	.001	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

INO80E–CESC (OS)

Open the CESC breakdown →