INO80E

Across TCGA pan-cancer cohorts, INO80E mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated INO80E data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher INO80E mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated INO80E expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LUAD, CCRCC, and LSCC are the cancer types where INO80E mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.444	0.864	.010	14	view →
CCRCC	OS	Median	II,III,IV	0.584	0.904	.016	10	view →
LSCC	DFS	Tertile	All	0.884	0.723	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

INO80E–LUAD (OS)

Open the LUAD breakdown →