INO80E

Across TCGA patient cohorts, INO80E mutation is significantly associated with the RNA expression of many other genes, with 372 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INO80E-associated genes across cancer lineages are TRAJ47, RN7SL337P, and TUBAP10. Each is linked with INO80E in more than 1 cancer types. Because this analysis shows association rather than direction, both INO80E-to-partner and partner-to-INO80E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ47 grouped by INO80E-low versus INO80E-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80E→partner) and Y-score (partner→INO80E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAJ47 →	+0.730	+2.842	<.001	.002	3	2
CESC	RN7SL337P →	+0.214	+5.144	<.001	.003	3	1
CESC	TUBAP10 →	+0.097	+4.996	<.001	.002	3	1
CESC	OR5M14P →	+0.053	+4.539	<.001	.008	3	1
CESC	RNA5SP67 →	+0.644	+4.601	<.001	.004	3	1
CESC	CYP4A43P →	+0.404	+5.837	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 372 associations by consensus.

TRAJ47 by INO80E expression — UCEC

Explore this box plot interactively →