INO80E

Across TCGA patient cohorts, INO80E mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INO80E-associated genes across cancer lineages are Notch1 and Annexin-1. Each is linked with INO80E in more than 1 cancer types. Because this analysis shows association rather than direction, both INO80E-to-partner and partner-to-INO80E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by INO80E-low versus INO80E-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80E→partner) and Y-score (partner→INO80E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.319	+2.820	<.001	.035	3	1
UCEC	Annexin-1 →	+0.920	+2.827	.004	.035	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Notch1 by INO80E expression — UCEC

Explore this box plot interactively →