INO80E

Across TCGA cell cohorts, INO80E RNA expression is significantly associated with the go_rna of many other GO terms, with 4,235 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INO80E-associated GO terms across cancer lineages are Regulation of cell cycle checkpoint, Regulation of macrophage proliferation, and Regulation of mitotic metaphase/anaphase transition. Each is linked with INO80E in more than 10 cancer types. Because this analysis shows association rather than direction, both INO80E-to-partner and partner-to-INO80E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell cycle checkpoint grouped by INO80E-low versus INO80E-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80E→partner) and Y-score (partner→INO80E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of cell cycle checkpoint →	+0.103	+0.905	.002	.001	3	11
KIDNEY	Regulation of macrophage proliferation →	+0.266	+0.652	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic metaphase/anaphase transition →	+0.111	+0.806	.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.177	+1.040	.002	<.001	3	10
KIDNEY	Positive regulation of macrophage proliferation →	+0.248	+0.697	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of metaphase/anaphase transition of cell cycle →	+0.107	+0.801	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,235 associations by consensus.

Regulation of cell cycle checkpoint by INO80E expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →