INO80E

Across TCGA cell cohorts, INO80E mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INO80E-associated genes across cancer lineages are TDRD15, GJD2, and OR1D2. Each is linked with INO80E in more than 1 cancer types. Because this analysis shows association rather than direction, both INO80E-to-partner and partner-to-INO80E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TDRD15 grouped by INO80E-low versus INO80E-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80E→partner) and Y-score (partner→INO80E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TDRD15 →	+0.453	+4.734	<.001	.002	3	1
LARGE_INTESTINE	GJD2 →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR1D2 →	+0.011	+4.022	<.001	.006	3	1
BLOOD_Leukemia	KRT71 →	+0.066	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TDRD15 by INO80E expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →