INO80D

Across TCGA patient cohorts, INO80D mutation is significantly associated with the RNA expression of many other genes, with 3,316 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INO80D-associated genes across cancer lineages are BCCIP, KNSTRN, and PWP1. Each is linked with INO80D in more than 3 cancer types. Because this analysis shows association rather than direction, both INO80D-to-partner and partner-to-INO80D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCCIP grouped by INO80D-low versus INO80D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80D→partner) and Y-score (partner→INO80D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BCCIP →	+0.434	+3.052	<.001	<.001	3	4
UCEC	KNSTRN →	+0.696	+2.584	<.001	<.001	3	4
UCEC	PWP1 →	+0.334	+3.938	.001	<.001	3	4
UCEC	UBE2N →	+0.446	+2.233	<.001	<.001	3	4
SKCM	CALR →	+0.451	+3.719	.006	<.001	3	3
UCEC	PHF5A →	+0.599	+2.584	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,316 associations by consensus.

BCCIP by INO80D expression — UCEC

Explore this box plot interactively →