INO80B

Across TCGA pan-cancer cohorts, INO80B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated INO80B data layer compared with 25 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher INO80B mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated INO80B expression acts as an unfavorable survival marker, although some lineages such as HNSC and OV show a favorable association.

HNSC, OV, and PDAC are the cancer types where INO80B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	1.000	0.856	.008	23	view →
OV	DFS	Quartile	All	1.000	0.202	.042	12	view →
PDAC	DFS	Quartile	All	0.547	0.209	.006	11	view →
LSCC	DFS	Quartile	All	0.402	1.000	.014	6	view →
LUAD	DFS	Median	All	1.000	0.582	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

INO80B–HNSC (DFS)

Open the HNSC breakdown →