INO80B

Across TCGA patient cohorts, INO80B protein abundance is significantly associated with the RNA expression of many other genes, with 6,259 significant associations in total. GBM shows the largest number of these associations.

The most reproducible INO80B-associated genes across cancer lineages are SPTBN2, ADA2, and LINC02210. Each is linked with INO80B in more than 3 cancer types. Because this analysis shows association rather than direction, both INO80B-to-partner and partner-to-INO80B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INO80B versus SPTBN2 in LSCC, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80B→partner) and Y-score (partner→INO80B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPTBN2 →	+1.912	+1.337	<.001	<.001	3	4
UCEC	ADA2 →	-1.211	-0.894	.001	.001	3	3
LSCC	LINC02210 →	+1.012	+1.057	.003	.004	3	3
HNSC	RN7SL12P →	+1.513	+1.141	<.001	<.001	3	3
LSCC	BCDIN3D-AS1 →	+0.685	+1.210	.006	<.001	3	3
HNSC	RNF225 →	+0.924	+0.747	.009	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,259 associations by consensus.

INO80B vs SPTBN2 — LSCC

Explore this scatter interactively →