INO80B

Across TCGA patient cohorts, INO80B mutation is significantly associated with the RNA expression of many other genes, with 1,348 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INO80B-associated genes across cancer lineages are CCNG1P1, MIR6803, and IGHD4-17. Each is linked with INO80B in more than 1 cancer types. Because this analysis shows association rather than direction, both INO80B-to-partner and partner-to-INO80B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCNG1P1 grouped by INO80B-low versus INO80B-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80B→partner) and Y-score (partner→INO80B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CCNG1P1 →	+0.169	+5.069	<.001	.008	3	2
HNSC	MIR6803 →	+0.672	+6.936	<.001	<.001	3	2
UCEC	IGHD4-17 →	+0.685	+2.714	<.001	.005	3	2
SCLC	TAS2R7 →	+0.132	+5.624	<.001	.003	3	1
SCLC	LGALS16 →	+0.266	+4.847	<.001	.009	3	1
UCEC	RAP2CP1 →	+0.607	+3.459	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,348 associations by consensus.

CCNG1P1 by INO80B expression — HNSC

Explore this box plot interactively →