INO80-AS1

Across TCGA pan-cancer cohorts, INO80-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated INO80-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher INO80-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated INO80-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and LAML show a favorable association.

ACC, OV, and UCEC are the cancer types where INO80-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Quartile	All	0.229	0.614	<.001	67	view →
OV	DFS	Tertile	II,III,IV	0.210	0.119	.009	44	view →
UCEC	OS	Quartile	All	0.887	0.951	.001	42	view →
KIRC	DFS	Quartile	All	0.550	0.703	.004	41	view →
PAAD	OS	Median	II,III,IV	0.253	0.498	.002	37	view →
UVM	DFS	Quartile	III,IV	0.260	0.785	.001	35	view →
LAML	DFS	Median	All	0.551	0.234	.001	12	view →
BRCA	DFS	Quartile	III,IV	0.849	0.693	.017	10	view →
MESO	OS	Median	IV	0.813	0.374	.012	9	view →
GBM	OS	Quartile	All	0.340	0.221	.010	9	view →
TGCT	DFS	Quartile	All	0.973	0.803	.008	6	view →
LUAD	OS	Tertile	All	0.784	0.850	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

INO80-AS1–ACC (DFS)

Open the ACC breakdown →