INKA2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, INKA2 mutation is significantly associated with the RNA expression of many other genes, with 2,032 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INKA2-associated genes across cancer lineages are GOLGA6L11P, TRAJ42, and MIR4802. Each is linked with INKA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both INKA2-to-partner and partner-to-INKA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INKA2→partner) and Y-score (partner→INKA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGOLGA6L11P →+0.016+3.555<.001.00233
COADTRAJ42 →+0.927+4.415.003.00632
COADMIR4802 →+0.991+4.446.003.00632
BLCAMIR3130-2 →+0.368+3.971.001.00532
SKCMRAB28P4 →+0.089+5.900<.001<.00132
BRCALSM6P2 →+0.206+4.883<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,032 associations by consensus.

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