Across TCGA patient cohorts, INKA2 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INKA2-associated genes across cancer lineages are CD8+ Tcm, Endothelial cells, and lymphatic Endothelial cells. Each is linked with INKA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both INKA2-to-partner and partner-to-INKA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INKA2→partner) and Y-score (partner→INKA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.024	+2.128	.002	.019	3	3
UCEC	Endothelial cells →	-0.036	-2.313	.023	.035	3	1
UCEC	lymphatic Endothelial cells →	-0.022	-2.544	.022	.011	3	1
UCEC	mv Endothelial cells →	-0.023	-2.321	.019	.035	3	1
UCEC	Basophils →	+0.160	+1.807	.022	.028	3	1
UCEC	pDC →	+0.071	+3.491	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

INKA2 survival (RNA) · tumor vs normal (RNA) · all INKA2 data types