Across TCGA cell cohorts, INKA2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible INKA2-associated genes across cancer lineages are IZUMO1R, OR56A5, and RBMY1J. Each is linked with INKA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both INKA2-to-partner and partner-to-INKA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INKA2→partner) and Y-score (partner→INKA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	IZUMO1R →	+0.053	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	OR56A5 →	+0.045	+4.736	<.001	.009	3	1
SKIN	RBMY1J →	+0.006	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

INKA2 survival (RNA) · tumor vs normal (RNA) · all INKA2 data types