Across TCGA pan-cancer cohorts, INKA1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated INKA1 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher INKA1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated INKA1 expression acts as an unfavorable survival marker.

UCEC and PRAD are the cancer types where INKA1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.321	0.680	<.001	18	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: INKA1 tumor-vs-normal RNA expression · all INKA1 data types