INHBE

Across TCGA patient cohorts, INHBE protein abundance is significantly associated with the RNA expression of many other genes, with 3,220 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible INHBE-associated genes across cancer lineages are MTMR9LP, PRX, and KLF1. Each is linked with INHBE in more than 2 cancer types. Because this analysis shows association rather than direction, both INHBE-to-partner and partner-to-INHBE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INHBE versus MTMR9LP in OV, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INHBE→partner) and Y-score (partner→INHBE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MTMR9LP →	+0.988	+0.742	<.001	<.001	3	3
OV	PRX →	+0.453	+0.431	.002	.002	3	2
OV	KLF1 →	+0.246	+0.716	.003	.002	3	2
OV	CHRNE →	+0.503	+0.699	<.001	<.001	3	2
COAD	ARHGAP22 →	+0.593	+0.349	<.001	.006	3	2
OV	SYT11 →	+1.202	+0.608	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,220 associations by consensus.

INHBE vs MTMR9LP — OV

Explore this scatter interactively →