INHBE

Across TCGA cell cohorts, INHBE RNA expression is significantly associated with the go_rna of many other GO terms, with 3,401 significant associations in total. BONE shows the largest number of these associations.

The most reproducible INHBE-associated GO terms across cancer lineages are L-amino acid biosynthetic process, Response to endoplasmic reticulum stress, and PERK-mediated unfolded protein response. Each is linked with INHBE in more than 11 cancer types. Because this analysis shows association rather than direction, both INHBE-to-partner and partner-to-INHBE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-amino acid biosynthetic process grouped by INHBE-low versus INHBE-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INHBE→partner) and Y-score (partner→INHBE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	L-amino acid biosynthetic process →	+0.128	+2.345	<.001	<.001	3	12
BLOOD_Myeloma	Response to endoplasmic reticulum stress →	+0.083	+3.501	<.001	<.001	3	11
BLOOD_Myeloma	PERK-mediated unfolded protein response →	+0.201	+3.473	<.001	<.001	3	11
BONE	Regulation of translation in response to stress →	+0.114	+1.673	<.001	<.001	3	10
LARGE_INTESTINE	L-serine biosynthetic process →	+0.250	+1.170	<.001	<.001	3	10
BONE	L-glutamate biosynthetic process →	+0.237	+2.497	.004	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,401 associations by consensus.

L-amino acid biosynthetic process by INHBE expression — BLOOD_Lymphoma

Explore this box plot interactively →