INHBC

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, INHBC protein abundance is significantly associated with the RNA expression of many other genes, with 5,422 significant associations in total. GBM shows the largest number of these associations.

The most reproducible INHBC-associated genes across cancer lineages are CDO1, ANGPT1, and PTH1R. Each is linked with INHBC in more than 3 cancer types. Because this analysis shows association rather than direction, both INHBC-to-partner and partner-to-INHBC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INHBC versus CDO1 in UCEC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INHBC→partner) and Y-score (partner→INHBC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCDO1 →+1.820+1.111.003.00624
UCECANGPT1 →+1.112+0.905.004<.00133
UCECPTH1R →+1.565+1.078<.001.00224
UCECSRPX →+2.168+1.268<.001<.00133
UCECMEIS3 →+1.766+1.063.001.00233
CCRCCCOLEC12 →+1.043+0.857<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,422 associations by consensus.

INHBC vs CDO1 — UCEC

Per-sample scatter of INHBC vs CDO1 in UCEC (Pearson r = 0.50).

Explore this scatter interactively →

Exploration