INHBC

Across TCGA patient cohorts, INHBC mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INHBC-associated genes across cancer lineages are Preadipocytes, pDC, and aDC. Each is linked with INHBC in more than 2 cancer types. Because this analysis shows association rather than direction, both INHBC-to-partner and partner-to-INHBC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Preadipocytes grouped by INHBC-low versus INHBC-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INHBC→partner) and Y-score (partner→INHBC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Preadipocytes →	+0.029	+4.491	.018	<.001	3	1
UCEC	pDC →	+0.088	+3.180	.001	.010	1	3
UCEC	aDC →	+0.150	+3.180	<.001	.010	1	1
UCEC	pro B-cells →	+0.161	+3.169	.006	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Preadipocytes by INHBC expression — COAD

Explore this box plot interactively →