INHBC

Across TCGA cell cohorts, INHBC RNA expression is significantly associated with the go_rna of many other GO terms, with 2,179 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INHBC-associated GO terms across cancer lineages are PERK-mediated unfolded protein response, Protein polyubiquitination, and RNA catabolic process. Each is linked with INHBC in more than 9 cancer types. Because this analysis shows association rather than direction, both INHBC-to-partner and partner-to-INHBC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PERK-mediated unfolded protein response grouped by INHBC-low versus INHBC-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INHBC→partner) and Y-score (partner→INHBC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	PERK-mediated unfolded protein response →	+0.193	+1.534	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.063	+0.121	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	RNA catabolic process →	+0.057	+0.103	.001	.001	2	9
BONE	Negative regulation of gene expression, epigenetic →	+0.090	+0.153	<.001	.001	2	8
URINARY_TRACT	Regulation of myoblast fusion →	+0.098	+0.285	<.001	<.001	3	7
URINARY_TRACT	Actin-mediated cell contraction →	-0.115	-0.225	.002	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,179 associations by consensus.

PERK-mediated unfolded protein response by INHBC expression — BLOOD_Myeloma

Explore this box plot interactively →