Across TCGA pan-cancer cohorts, INHBA-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated INHBA-AS1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher INHBA-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated INHBA-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and KIRC show a favorable association.

THCA, MESO, and STAD are the cancer types where INHBA-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	All	0.882	0.993	<.001	60	view →
MESO	OS	Tertile	All	0.231	0.471	<.001	54	view →
STAD	OS	Median	All	0.301	0.553	<.001	50	view →
LGG	OS	Tertile	All	0.635	0.406	<.001	43	view →
CESC	DFS	Tertile	All	0.753	0.879	.002	38	view →
HNSC	DFS	Tertile	All	0.653	0.784	<.001	37	view →
KIRC	DFS	Median	All	0.859	0.726	.001	31	view →
LUSC	DFS	Median	II,III,IV	0.566	0.866	.004	30	view →
DLBC	OS	Median	II,III,IV	0.291	1.000	.006	24	view →
BLCA	DFS	Tertile	All	0.456	0.572	.009	18	view →
ESCA	OS	Median	All	1.000	0.427	.007	17	view →
LUAD	OS	Quartile	II,III,IV	0.826	0.594	.002	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration

Same gene, other analysis: INHBA-AS1 tumor-vs-normal RNA expression · all INHBA-AS1 data types