INHA

Across TCGA patient cohorts, INHA mutation is significantly associated with the RNA expression of many other genes, with 253 significant associations in total. COAD shows the largest number of these associations.

The most reproducible INHA-associated genes across cancer lineages are MIR4524B, CXCL13, and RNA5SP247. Each is linked with INHA in more than 1 cancer types. Because this analysis shows association rather than direction, both INHA-to-partner and partner-to-INHA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4524B grouped by INHA-low versus INHA-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INHA→partner) and Y-score (partner→INHA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR4524B →	+0.265	+3.567	<.001	.003	3	2
UCEC	CXCL13 →	+1.608	+2.700	.004	.006	3	2
UCEC	RNA5SP247 →	+0.421	+2.264	.003	.002	3	2
UCEC	CDH12P1 →	+0.035	+4.360	<.001	.004	3	2
SKCM	BCAR1P2 →	+0.043	+2.917	<.001	.002	3	2
BRCA	MIR6737 →	+0.678	+5.506	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 253 associations by consensus.

MIR4524B by INHA expression — COAD

Explore this box plot interactively →