INHA

Across TCGA cell cohorts, INHA mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INHA-associated genes across cancer lineages are MS4A10, COX6A2, and BPIFB6. Each is linked with INHA in more than 1 cancer types. Because this analysis shows association rather than direction, both INHA-to-partner and partner-to-INHA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A10 grouped by INHA-low versus INHA-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INHA→partner) and Y-score (partner→INHA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MS4A10 →	+0.013	+5.196	<.001	.005	3	1
LARGE_INTESTINE	COX6A2 →	+0.058	+3.700	<.001	.009	3	1
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR51D1 →	+0.009	+3.217	<.001	.006	3	1
LARGE_INTESTINE	KLK9 →	+0.125	+4.141	.003	<.001	3	1
LARGE_INTESTINE	LINGO4 →	+0.156	+3.584	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

MS4A10 by INHA expression — OVARY

Explore this box plot interactively →