ING5

Across TCGA pan-cancer cohorts, ING5 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ING5 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher ING5 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ING5 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

LSCC, HNSC, and PDAC are the cancer types where ING5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	All	0.953	0.721	.002	22	view →
HNSC	DFS	Quartile	All	0.739	0.470	.010	9	view →
PDAC	OS	Tertile	II,III,IV	0.603	0.266	.018	8	view →
CCRCC	OS	Median	II,III,IV	0.454	1.000	.014	5	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ING5–LSCC (OS)

Open the LSCC breakdown →