ING5

Across TCGA cell cohorts, ING5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,233 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ING5-associated GO terms across cancer lineages are DNA replication-dependent chromatin disassembly, Subtelomeric heterochromatin formation, and Otolith mineralization. Each is linked with ING5 in more than 16 cancer types. Because this analysis shows association rather than direction, both ING5-to-partner and partner-to-ING5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication-dependent chromatin disassembly grouped by ING5-low versus ING5-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ING5→partner) and Y-score (partner→ING5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DNA replication-dependent chromatin disassembly →	+0.166	+0.819	<.001	<.001	3	17
BONE	Subtelomeric heterochromatin formation →	+0.113	+0.815	<.001	<.001	3	16
OESOPHAGUS	Otolith mineralization →	+0.150	+1.137	<.001	<.001	3	16
BLOOD_Myeloma	Regulation of interleukin-6 production →	-0.088	-0.997	.002	<.001	3	14
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.086	+1.062	<.001	<.001	3	14
BONE	Epigenetic regulation of gene expression →	+0.072	+0.811	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,233 associations by consensus.

DNA replication-dependent chromatin disassembly by ING5 expression — LUNG_SCLC

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