ING3

Across TCGA pan-cancer cohorts, ING3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ING3 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ING3 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ING3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where ING3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	III,IV	0.967	0.626	.002	40	view →
LSCC	OS	Tertile	All	0.971	0.692	.002	25	view →
LUAD	DFS	Median	III,IV	0.432	0.925	.047	3	view →
HNSC	DFS	Median	III,IV	0.935	1.000	.032	3	view →
GBM	OS	Median	All	0.472	0.272	.007	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ING3–CCRCC (OS)

Open the CCRCC breakdown →