ING3

Across TCGA cell cohorts, ING3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,949 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ING3-associated GO terms across cancer lineages are Positive regulation of DNA recombination, Regulation of double-strand break repair via homologous recombination, and Positive regulation of double-strand break repair via homologous recombination. Each is linked with ING3 in more than 13 cancer types. Because this analysis shows association rather than direction, both ING3-to-partner and partner-to-ING3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA recombination grouped by ING3-low versus ING3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ING3→partner) and Y-score (partner→ING3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of DNA recombination →	+0.093	+0.896	<.001	<.001	3	14
BLOOD_Lymphoma	Regulation of double-strand break repair via homologous recombination →	+0.078	+1.007	<.001	<.001	3	14
LUNG_NSCLC_LUAD	Positive regulation of double-strand break repair via homologous recombination →	+0.086	+0.783	<.001	<.001	3	14
SOFT_TISSUE	Replication fork processing →	+0.094	+1.096	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of double-strand break repair →	+0.081	+1.207	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitotic chromosome condensation →	+0.147	+0.941	.004	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,949 associations by consensus.

Positive regulation of DNA recombination by ING3 expression — SOFT_TISSUE

Explore this box plot interactively →