ING2

Across TCGA patient cohorts, ING2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,047 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ING2-associated genes across cancer lineages are GPRC5B, NEDD9, and C12orf29. Each is linked with ING2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ING2-to-partner and partner-to-ING2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ING2 versus GPRC5B in HNSC, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ING2→partner) and Y-score (partner→ING2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GPRC5B →	-1.403	-0.695	.009	.009	3	3
HNSC	NEDD9 →	-0.758	-0.512	.004	.007	3	2
UCEC	C12orf29 →	+0.376	+0.419	.003	.006	3	2
UCEC	GLIPR1 →	-0.636	-0.632	.001	.002	3	2
GBM	LRRC4C →	-1.281	-0.560	.002	.009	3	2
UCEC	SERPING1 →	-1.315	-0.725	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,047 associations by consensus.

ING2 vs GPRC5B — HNSC

Explore this scatter interactively →