ING2

Across TCGA cell cohorts, ING2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,627 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ING2-associated GO terms across cancer lineages are Negative regulation of stem cell population maintenance, Positive regulation of stem cell population maintenance, and DNA synthesis involved in DNA replication. Each is linked with ING2 in more than 14 cancer types. Because this analysis shows association rather than direction, both ING2-to-partner and partner-to-ING2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of stem cell population maintenance grouped by ING2-low versus ING2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ING2→partner) and Y-score (partner→ING2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of stem cell population maintenance →	+0.100	+1.037	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of stem cell population maintenance →	+0.103	+1.094	<.001	<.001	3	14
BLOOD_Lymphoma	DNA synthesis involved in DNA replication →	+0.084	+0.972	<.001	<.001	3	13
BLOOD_Leukemia	Error-prone translesion synthesis →	+0.083	+0.530	<.001	<.001	3	11
BONE	Depurination →	+0.147	+0.810	.001	.003	2	12
OVARY	DNA damage tolerance →	+0.068	+0.723	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,627 associations by consensus.

Negative regulation of stem cell population maintenance by ING2 expression — BREAST

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