ING2

Across TCGA cell cohorts, ING2 mutation is significantly associated with the mutation status of many other genes, with 834 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ING2-associated genes across cancer lineages are SLC5A1, RSPH6A, and HAS1. Each is linked with ING2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ING2-to-partner and partner-to-ING2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC5A1 grouped by ING2-low versus ING2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ING2→partner) and Y-score (partner→ING2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	SLC5A1 →	+4.415	+4.977	.007	.007	1	2
OVARY	RSPH6A →	+5.415	+5.415	.004	.004	1	2
OVARY	HAS1 →	+4.415	+4.977	.007	.007	1	2
OVARY	FKBP8 →	+5.415	+5.415	.004	.004	1	2
OVARY	KRT32 →	+5.415	+5.415	.004	.004	1	2
OVARY	TENT4A →	+5.415	+5.415	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 834 associations by consensus.

SLC5A1 by ING2 expression — OVARY

Explore this box plot interactively →