ING1

Across TCGA pan-cancer cohorts, ING1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ING1 data layer compared with 24 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ING1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ING1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

HNSC, LUAD, and PDAC are the cancer types where ING1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.581	0.875	.003	16	view →
LUAD	OS	Quartile	All	1.000	0.566	.004	13	view →
PDAC	OS	Tertile	III,IV	0.916	0.434	.002	12	view →
CCRCC	OS	Tertile	IV	0.961	0.199	.036	6	view →
LSCC	OS	Median	III,IV	0.871	0.515	.021	4	view →
GBM	OS	Tertile	All	0.629	0.313	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ING1–HNSC (OS)

Open the HNSC breakdown →