ING1

Across TCGA patient cohorts, ING1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,949 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ING1-associated genes across cancer lineages are KLF12, PGBD1, and RHOV. Each is linked with ING1 in more than 4 cancer types. Because this analysis shows association rather than direction, both ING1-to-partner and partner-to-ING1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ING1 versus KLF12 in HNSC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ING1→partner) and Y-score (partner→ING1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KLF12 →	+0.702	+0.250	<.001	.002	3	5
LSCC	PGBD1 →	+0.750	+0.327	.001	.007	3	5
LSCC	RHOV →	-0.999	-0.251	.002	.004	3	4
LSCC	FANCL →	+0.670	+0.409	<.001	.001	3	4
UCEC	PTBP2 →	+0.477	+0.232	.002	.005	3	4
LSCC	USP1 →	+0.577	+0.355	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,949 associations by consensus.

ING1 vs KLF12 — HNSC

Explore this scatter interactively →