ING1

Across TCGA cell cohorts, ING1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,156 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ING1-associated GO terms across cancer lineages are Negative regulation of stem cell population maintenance, Positive regulation of stem cell population maintenance, and Negative regulation of calcium ion export across plasma membrane. Each is linked with ING1 in more than 14 cancer types. Because this analysis shows association rather than direction, both ING1-to-partner and partner-to-ING1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of stem cell population maintenance grouped by ING1-low versus ING1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ING1→partner) and Y-score (partner→ING1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of stem cell population maintenance →	+0.088	+1.283	<.001	<.001	3	15
LUNG_SCLC	Positive regulation of stem cell population maintenance →	+0.087	+1.086	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.075	+0.804	<.001	<.001	3	14
LUNG_SCLC	Regulation of stem cell population maintenance →	+0.072	+1.064	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.093	+0.747	<.001	<.001	3	14
CNS	Regulation of cell cycle G1/S phase transition →	+0.055	+0.743	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,156 associations by consensus.

Negative regulation of stem cell population maintenance by ING1 expression — LUNG_SCLC

Explore this box plot interactively →