Across TCGA patient cohorts, INF2 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INF2-associated genes across cancer lineages are Caspase-7-cleavedD198, Annexin-1, and Cyclin-B1. Each is linked with INF2 in more than 3 cancer types. Because this analysis shows association rather than direction, both INF2-to-partner and partner-to-INF2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INF2→partner) and Y-score (partner→INF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.984	+1.882	.002	.031	3	4
UCEC	Annexin-1 →	+0.635	+3.926	.001	<.001	3	3
UCEC	Cyclin-B1 →	+0.666	+2.700	.001	.006	2	4
UCEC	IGFBP2 →	-0.559	-2.000	.022	.030	3	2
UCEC	PRDX1 →	+0.219	+2.662	.004	<.001	3	2
COAD	Rad50 →	-0.328	-3.000	.001	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

INF2 survival (RNA) · tumor vs normal (RNA) · all INF2 data types