INCA1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, INCA1 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INCA1-associated genes across cancer lineages are MIR4777, MIR5688, and ELOCP4. Each is linked with INCA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both INCA1-to-partner and partner-to-INCA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INCA1→partner) and Y-score (partner→INCA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMIR4777 →+0.618+4.568<.001.00431
BLCAMIR5688 →+0.740+5.320<.001.00131
BRCAELOCP4 →+0.114+8.471<.001.00531
BRCATSPY25P →+0.054+8.471<.001.00531
UCECSNORD11B →+0.704+2.798.001.00831
SKCMRN7SL601P →+0.249+7.816<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

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