INAFM2

Across TCGA cell cohorts, INAFM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,282 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INAFM2-associated GO terms across cancer lineages are Protein localization to endoplasmic reticulum, Regulation of calcineurin-NFAT signaling cascade, and Regulation of calcineurin-mediated signaling. Each is linked with INAFM2 in more than 7 cancer types. Because this analysis shows association rather than direction, both INAFM2-to-partner and partner-to-INAFM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to endoplasmic reticulum grouped by INAFM2-low versus INAFM2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INAFM2→partner) and Y-score (partner→INAFM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Protein localization to endoplasmic reticulum →	+0.055	+0.688	.005	.006	3	8
KIDNEY	Regulation of calcineurin-NFAT signaling cascade →	+0.157	+1.221	<.001	<.001	3	8
KIDNEY	Regulation of calcineurin-mediated signaling →	+0.159	+1.221	<.001	<.001	3	8
KIDNEY	Regulation of cell-matrix adhesion →	+0.085	+1.325	.001	<.001	3	7
CNS	Regulation of actin filament bundle assembly →	+0.049	+0.647	.003	.001	3	7
CNS	Gastrulation →	+0.053	+0.445	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,282 associations by consensus.

Protein localization to endoplasmic reticulum by INAFM2 expression — BLOOD_Leukemia

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