INAFM1

Across TCGA patient cohorts, INAFM1 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INAFM1-associated genes across cancer lineages are RNA5SP516, RNU6-1082P, and RNU6-354P. Each is linked with INAFM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both INAFM1-to-partner and partner-to-INAFM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP516 grouped by INAFM1-low versus INAFM1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INAFM1→partner) and Y-score (partner→INAFM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP516 →	+0.677	+4.937	<.001	.005	3	1
UCEC	RNU6-1082P →	+0.469	+4.551	<.001	.009	3	1
UCEC	RNU6-354P →	+0.626	+5.223	<.001	.001	3	1
UCEC	RNU6-1296P →	+0.598	+6.470	<.001	<.001	3	1
UCEC	RNU6-147P →	+0.422	+4.551	.004	.009	3	1
UCEC	RNU6-136P →	+0.761	+4.188	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

RNA5SP516 by INAFM1 expression — UCEC

Explore this box plot interactively →