INA

Across TCGA cell cohorts, INA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,375 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INA-associated GO terms across cancer lineages are Postsynaptic intermediate filament cytoskeleton organization, Microtubule cytoskeleton organization involved in mitosis, and Nuclear-transcribed mRNA catabolic process. Each is linked with INA in more than 14 cancer types. Because this analysis shows association rather than direction, both INA-to-partner and partner-to-INA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Postsynaptic intermediate filament cytoskeleton organization grouped by INA-low versus INA-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INA→partner) and Y-score (partner→INA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Postsynaptic intermediate filament cytoskeleton organization →	+2.013	+3.155	<.001	.004	3	15
BREAST	Microtubule cytoskeleton organization involved in mitosis →	+0.080	+1.021	<.001	.007	3	9
LUNG_NSCLC_LUAD	Nuclear-transcribed mRNA catabolic process →	+0.035	+1.966	.001	.001	2	9
LUNG_SCLC	U2-type prespliceosome assembly →	+0.102	+2.071	<.001	.009	3	8
BREAST	Regulation of mRNA processing →	+0.076	+0.972	<.001	<.001	3	8
BONE	Regulation of chromatin organization →	+0.119	+2.534	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,375 associations by consensus.

Postsynaptic intermediate filament cytoskeleton organization by INA expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →