IMPG2

Across TCGA patient cohorts, IMPG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,062 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IMPG2-associated proteins across cancer lineages are AP2A1, CLUH, and MRPL39. Each is linked with IMPG2 in more than 4 cancer types. Because this analysis shows association rather than direction, both IMPG2-to-partner and partner-to-IMPG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IMPG2 versus AP2A1 in PDAC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPG2→partner) and Y-score (partner→IMPG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	AP2A1 →	+0.230	+0.290	<.001	.001	3	5
LSCC	CLUH →	-0.253	-0.184	<.001	<.001	3	4
BRCA	MRPL39 →	-0.268	-0.238	<.001	<.001	3	4
COAD	MRPS23 →	-0.354	-0.149	.001	.002	3	4
COAD	MRPS7 →	-0.410	-0.113	<.001	<.001	3	4
GBM	PPP1R9B →	+0.271	+0.438	<.001	.004	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,062 associations by consensus.

IMPG2 vs AP2A1 — PDAC

Explore this scatter interactively →