IMPG2

Across TCGA patient cohorts, IMPG2 protein abundance is significantly associated with the RNA expression of many other genes, with 769 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IMPG2-associated genes across cancer lineages are CALB2, SH2D5, and CRYBB2P1. Each is linked with IMPG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IMPG2-to-partner and partner-to-IMPG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IMPG2 versus CALB2 in GBM, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPG2→partner) and Y-score (partner→IMPG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CALB2 →	-1.958	-0.442	<.001	.001	3	2
GBM	SH2D5 →	-1.080	-0.604	<.001	<.001	3	2
UCEC	CRYBB2P1 →	-0.595	-0.797	.001	.001	3	1
UCEC	SH3BP1 →	-0.362	-0.596	.007	.002	3	1
UCEC	DMC1 →	-0.460	-0.645	.006	.004	3	1
UCEC	CACNA1I →	-0.640	-0.635	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 769 associations by consensus.

IMPG2 vs CALB2 — GBM

Explore this scatter interactively →