IMPG2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IMPG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,979 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IMPG2-associated GO terms across cancer lineages are Endosomal transport, Macroautophagy, and Negative regulation of myoblast fusion. Each is linked with IMPG2 in more than 10 cancer types. Because this analysis shows association rather than direction, both IMPG2-to-partner and partner-to-IMPG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by IMPG2-low versus IMPG2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPG2→partner) and Y-score (partner→IMPG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTEndosomal transport →+0.069+0.122<.001.002311
STOMACHMacroautophagy →+0.086+0.156<.001.009311
UPPER_AERODIGESTIVE_TRACTNegative regulation of myoblast fusion →+0.125+0.120<.001.003311
STOMACHProcess utilizing autophagic mechanism →+0.087+0.164<.001.005311
STOMACHAutophagy →+0.087+0.164<.001.005311
LIVERVacuole organization →+0.046+0.073.005.006311
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,979 associations by consensus.

Endosomal transport by IMPG2 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of Endosomal transport in IMPG2-low vs IMPG2-high samples in UPPER_AERODIGESTIVE_TRACT.

Explore this box plot interactively →

Exploration