IMPG1

Across TCGA patient cohorts, IMPG1 protein abundance is significantly associated with the RNA expression of many other genes, with 969 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IMPG1-associated genes across cancer lineages are HEATR1, CLCN1, and URB2. Each is linked with IMPG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IMPG1-to-partner and partner-to-IMPG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IMPG1 versus HEATR1 in BRCA, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPG1→partner) and Y-score (partner→IMPG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HEATR1 →	+0.913	+0.630	.002	<.001	3	1
BRCA	CLCN1 →	-0.138	-0.605	.009	.002	3	1
BRCA	URB2 →	+0.816	+0.573	.005	.003	2	1
BRCA	HMGN2P30 →	+0.560	+0.573	<.001	.003	2	1
BRCA	PARK7P1 →	+0.813	+0.473	.009	<.001	2	1
BRCA	FAHD2B →	+1.568	+0.500	.005	.003	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 969 associations by consensus.

IMPG1 vs HEATR1 — BRCA

Explore this scatter interactively →