IMPG1

Across TCGA cell cohorts, IMPG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,983 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IMPG1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of syncytium formation by plasma membrane fusion, and Negative regulation of Arp2/3 complex-mediated actin nucleation. Each is linked with IMPG1 in more than 9 cancer types. Because this analysis shows association rather than direction, both IMPG1-to-partner and partner-to-IMPG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by IMPG1-low versus IMPG1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPG1→partner) and Y-score (partner→IMPG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of myoblast fusion →	+0.094	+0.233	<.001	<.001	3	10
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.082	+0.171	<.001	.001	3	10
LUNG_NSCLC_LUSC	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.172	+0.102	.003	.001	3	10
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.088	+0.223	.001	<.001	3	9
LARGE_INTESTINE	Cilium or flagellum-dependent cell motility →	-0.103	-0.247	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.144	-0.284	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,983 associations by consensus.

Regulation of myoblast fusion by IMPG1 expression — BREAST

Explore this box plot interactively →