Across TCGA patient cohorts, IMPDH1P8 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,414 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IMPDH1P8-associated proteins across cancer lineages are GTF3C4, MSH6, and PHF3. Each is linked with IMPDH1P8 in more than 6 cancer types. Because this analysis shows association rather than direction, both IMPDH1P8-to-partner and partner-to-IMPDH1P8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IMPDH1P8→partner) and Y-score (partner→IMPDH1P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GTF3C4 →	+0.273	+0.527	<.001	<.001	3	7
LSCC	MSH6 →	+0.511	+0.737	<.001	<.001	3	7
LSCC	PHF3 →	+0.282	+0.784	<.001	<.001	3	6
GBM	PHF6 →	+0.449	+0.750	<.001	<.001	3	6
GBM	SAFB2 →	+0.259	+0.584	.005	.001	3	6
BRCA	CDC73 →	+0.338	+0.644	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,414 associations by consensus.

Exploration

IMPDH1P8 survival (RNA) · tumor vs normal (RNA) · all IMPDH1P8 data types